farmacodynamics cefquinme waa jiilka afraad ee antibiyootiga cephalosporin ee xayawaanka. iyadoo la joojinayo isku-dhafka gidaarka unugga si loo gaaro saameynta bakteeriyada, waxay leedahay firfircooni ballaaran oo bakteeriyada bakteeriyada, oo deggan β-lactamase. In vitro bacteriostatic tests ayaa muujiyay in cefquinoxime ay xasaasi u tahay bakteeriyada garaam-positive iyo garaam-negative ah. oo ay ku jiraan escherichia coli, citrobacter, klebsiella, pasteurella, proteus, salmonella, serratia marcescens, haemophilus bovis, actinomyces pyogenes, bacillus sPP, corynebacterium, staphylococcus aureus, streptococcus, bacterioid, streptococcus, bacterioid, clostritesodium, actinobacillin, actinomyces. erysipelas suis.
Doofaarka pharmacokinetic ayaa lagu duray 2mg of cefquinoxime intraday halkii 1kg ee miisaanka jidhka, iyo fiirsashada dhiiggu waxay gaadheen meeshii ugu sarraysay ka dib saacadaha 0.4, xoojinta ugu sarreysa waxay ahayd 5.93µg / ml, nus-nolosha nusku waxay ahayd qiyaastii 1.4 saacadood, iyo aagga hoos yimaada qalooca daroogada wuxuu ahaa 12.3/4 ml.
Antibiyootikada β-lactam waxaa loo isticmaalaa daawaynta cudurada neef-mareenka ee ay keento pasteurella multocida ama actinobacillus pleuropneumoniae.
Muruqa duridda: Hal qiyaas, 0.05ml halkii 1kg miisaanka jidhka ee lo'da, 0.08-0.12ml doofaarka, hal mar maalintii, 3-5 maalmood.
Wax falcelin xun laguma arag iyadoo loo eegayo isticmaalka iyo qiyaasta loo qoray.
1. Xoolaha xasaasiyadda ku leh antibiyootiga beta-lactam waa in aan la isticmaalin.
2. Ha la xidhiidhin alaabtan haddii aad xasaasiyad ku leedahay penicillin iyo antibiyootiga cephalosporin.
3. Si fiican u rux inta aanad isticmaalin.
