Pharmacodynamics cefquinme waa jiilka afraad ee antibiyootiga cephalosporin ee xayawaanka. Iyadoo la xakameynayo isku-dhafka gidaarka unugga si loo gaaro saameynta bakteeriyada, waxay leedahay firfircooni ballaaran oo bakteeriyada bakteeriyada, oo deggan β-lactamase. Tijaabooyin bacteriostatic ah oo gudaha vitro ah ayaa muujiyay in cefquinoxime ay xasaasi u tahay bakteeriyada garaam-positive iyo garaam-negative. Oo ay ku jiraan escherichia coli, citrobacter, klebsiella, pasteurella, proteus, salmonella, serratia marcescens, haemophilus bovis, actinomyces pyogenes, bacillus spp, corynebacterium, staphylococcus aureus, streptococcus, bacterioid, streptococcus, bacterioid, prestritesodium. erysipelas suis.
Doofaarka Pharmacokinetic ayaa lagu duray 2mg of cefquinoxime intraday halkii 1kg ee miisaanka jidhka, iyo xoojinta dhiiggu wuxuu gaadhay meeshii ugu sarreysay ka dib saacadaha 0.4, xoojinta ugu sarreysa waxay ahayd 5.93µg / ml, nus-nolosha baabi'inta waxay ahayd saacadaha 1.4, iyo aagga hoos yimaada qalooca daroogada wuxuu ahaa 12.34µml.
Antibiyootiga β-lactam waxaa loo isticmaalaa in lagu daweeyo cudurrada neef-mareenka ee ay keento Pasteurella multocida ama actinobacillus pleuropneumoniae.
Muruqa duridda: hal dose, 1mg halkii 1kg miisaanka jidhka, 1mg lo'da, 2mg idaha iyo doofaarro, hal mar maalintii, 3-5 maalmood.
Wax falcelin xun laguma arag iyadoo loo eegayo isticmaalka iyo qiyaasta loo qoray.
1. Xoolaha xasaasiyadda ku leh antibiyootiga beta-lactam waa in aan la isticmaalin.
2. Ha la xidhiidhin alaabtan haddii aad xasaasiyad ku leedahay penicillin iyo antibiyootiga cephalosporin.
3. Isticmaal oo hadda isku qas.
4. Alaabtani waxay soo saari doontaa xumbo marka la milmo, waana in fiiro gaar ah loo yeesho marka la shaqaynayo.
